SCHEMBL305218

SCHEMBL305218

CCCCCCc1ccccc1-c1csc(-c2cccs2)c1-c1ccccc1CCCCCC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
LIPG Q9Y5X9 1/20 0.38
ELANE P08246 2/20 0.34
CTSG P08311 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
CYSLTR2 Q9NS75 6/20 0.33
CYSLTR1 Q9Y271 6/20 0.33
GPR3 P46089 1/20 0.33
ADK P55263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11742662 0.82 LTA4H (0.55) LTA4HNR1H2NR1H3LIPGELANE
SCHEMBL1883229 0.81 KDM4E (0.38) LIPGELANECTSGKDM4EALDH1A1
SCHEMBL340368 0.77 KDM4E (0.41) LIPGKDM4EALDH1A1GAACYSLTR2
SCHEMBL4962707 0.77 KDM4E (0.41) LIPGKDM4EALDH1A1GAACYSLTR2
Boric Acid SCHEMBL1568581 0.77 LIPG (0.43) LIPGELANECTSGKDM4EALDH1A1
SCHEMBL8431931 0.76 LTA4H (0.40) LTA4HNR1H2NR1H3LIPGKDM4E
SCHEMBL19742067 0.74 KDM4E (0.39) LTA4HKDM4EALDH1A1GAA
SCHEMBL9619382 0.74 LIPG (0.62) NR1H2NR1H3LIPGCYSLTR2CYSLTR1
SCHEMBL8157124 0.74 LIPG (0.62) NR1H2NR1H3LIPGCYSLTR2CYSLTR1
SCHEMBL1921650 0.74 LIPG (0.62) NR1H2NR1H3LIPGCYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093588-B2 Siloxane-polymer dielectric compositions and related organic field-effect transistors NORTHWESTERN UNIVERSITY (US) 2012-01-10 US disclosed
US-20100019237-A1 Siloxane-Polymer Dielectric Compositions and Related Organic Field-Effect Transistors USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2010-01-28 US disclosed
US-7605394-B2 crosslinking reaction product of polyvinyl alcohol, vinyl alcohol-styrene copolymer with hexachlorosiloxane, 1,6-bis(trichlorosilyl)hexane, spin coating the product onto freshly oxygen plasma-treated doped silicon subtrate containing indium tin oxide layer, curing NORTHWESTERN UNIVERSITY (US) 2009-10-20 US disclosed
EP-1839339-A2 SILOXANE-POLYMER DIELECTRIC COMPOSITIONS AND RELATED ORGANIC FIELD-EFFECT TRANSISTORS Northwestern University (US) 2007-10-03 EP disclosed
WO-2006086082-A9 SILOXANE-POLYMER DIELECTRIC COMPOSITIONS AND RELATED ORGANIC FIELD-EFFECT TRANSISTORS UNIV NORTHWESTERN (US) 2006-09-28 WO disclosed
US-20060202195-A1 Siloxane-polymer dielectric compositions and related organic field-effect transistors USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2006-09-14 US disclosed
WO-2006086082-A2 SILOXANE-POLYMER DIELECTRIC COMPOSITIONS AND RELATED ORGANIC FIELD-EFFECT TRANSISTORS NORTHWESTERN UNIVERSITY (US) 2006-08-17 WO disclosed