Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | QARS1 | P47897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689117 | 0.62 | ALOX15 (0.43) | ALOX15BLMPMP22KMT2AQARS1 | |
| SCHEMBL2639252 | 0.62 | ALDH1A1 (0.37) | KMT2AKDM4EALDH1A1TDP1HSD17B10 | |
| SCHEMBL7037922 | 0.61 | ALDH1A1 (0.36) | KMT2AKDM4EALDH1A1TDP1HSD17B10 | |
| SCHEMBL2514287 | 0.61 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2A | |
| SCHEMBL375714 | 0.61 | KDM4E (0.33) | KDM4EALDH1A1TDP1 | |
| Glutamine SCHEMBL3052567 | 0.60 | ALOX15 (0.53) | ALOX15BLMPMP22KMT2AALDH1A1 | |
| Glutamine SCHEMBL3052571 | 0.60 | ALOX15 (0.53) | ALOX15BLMPMP22KMT2AALDH1A1 | |
| SCHEMBL9089896 | 0.60 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AQARS1 | |
| SCHEMBL711607 | 0.59 | ALOX15 (0.60) | ALOX15BLMPMP22KMT2AQARS1 | |
| SCHEMBL28313344 | 0.59 | ALOX15 (0.60) | ALOX15BLMPMP22KMT2AQARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100221781-A1 | CHO-K1 CELL LINE | HOFFMANN-LA ROCHE, INC. | 2010-09-02 | — | — | US | claimed |