SCHEMBL375714

SCHEMBL375714

NC(N)=Nn1cnc2c(=O)nc[nH]c21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ HPRT1 P00492 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27858602 0.74 ALDH1A1 (0.37) KDM4EALDH1A1TDP1HPRT1
SCHEMBL612167 0.73 ALDH1A1 (0.34) KDM4EALDH1A1TDP1HPRT1
SCHEMBL9010837 0.73 ALDH1A1 (0.35) KDM4EALDH1A1TDP1HPRT1
SCHEMBL2639252 0.73 ALDH1A1 (0.37) KDM4EALDH1A1TDP1HPRT1
SCHEMBL7037922 0.72 ALDH1A1 (0.36) KDM4EALDH1A1TDP1HPRT1
SCHEMBL28147771 0.71 ALDH1A1 (0.35) KDM4EALDH1A1TDP1HPRT1
SCHEMBL4404534 0.69 ALDH1A1 (0.34) KDM4EALDH1A1TDP1HPRT1
SCHEMBL7168417 0.69 ALDH1A1 (0.34) KDM4EALDH1A1TDP1HPRT1
SCHEMBL28004546 0.69 ALDH1A1 (0.34) KDM4EALDH1A1TDP1HPRT1
SCHEMBL28004456 0.69 ALDH1A1 (0.34) KDM4EALDH1A1TDP1HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212680-A1 NUCLEOPHOSMIN PROTEIN (NPM) MUTANTS, CORRESPONDING GENE SEQUENCES AND USES THEREOF FALINI BRUNANGELO (IT) 2023-07-06 — — US disclosed
CN-112898434-B Method for rapidly detecting E4P production capacity of strain to be detected and biosensor used by same 中国科学院天津工业生物技术研究所 2021-11-05 — — CN disclosed
CN-112898434-A Method for rapidly detecting E4P production capacity of strain to be detected and biosensor used by same 中国科学院天津工业生物技术研究所 2021-06-04 — — CN disclosed
US-20200032354-A1 NUCLEOPHOSMIN PROTEIN (NPM) MUTANTS, CORRESPONDING GENE SEQUENCES AND USES THEREOF CARDIFF ONCOLOGY, INC. 2020-01-30 — — US disclosed
EP-3284750-B1 NUCLEOPHOSMIN PROTEIN (NPM) MUTANTS, CORRESPONDING GENE SEQUENCES AND USES THEREOF FALINI BRUNANGELO (IT) 2019-09-11 — — EP disclosed
US-10155989-B2 Nucleophosmin protein (NPM) mutants, corresponding gene sequences and uses thereof CARDIFF ONCOLOGY, INC. 2018-12-18 — — US disclosed
US-20180119233-A1 NUCLEOPHOSMIN PROTEIN (NPM) MUTANTS, CORRESPONDING GENE SEQUENCES AND USES THEREOF CARDIFF ONCOLOGY, INC. 2018-05-03 — — US disclosed
EP-3284750-A1 NUCLEOPHOSMIN PROTEIN (NPM) MUTANTS, CORRESPONDING GENE SEQUENCES AND USES THEREOF Falini, Brunangelo (IT) 2018-02-21 — — EP disclosed
EP-2319865-B1 Nucleophosmin protein (NPM) mutants, corresponding gene sequences and uses thereof FALINI BRUNANGELO (IT) 2017-08-30 — — EP disclosed
US-9725767-B2 Nucleophosmin protein (NPM) mutants, corresponding gene sequences and uses thereof TROVAGENE, INC. (US) 2017-08-08 — — US disclosed
US-5593850-A Monitoring of industrial water quality using monoclonal antibodies to polymers NALCO CHEMICAL COMPANY (US) 1997-01-14 — — US disclosed
EP-0535347-B1 Monoclonal antibodies to sulfonated polymers NALCO CHEMICAL CO (US) 1996-10-02 — — EP disclosed
US-5489516-A INHIBITION THE BINDING CELL GROWTH FACTOR TO CELL RECEPTOR BOARD OF REGEANT OF THE UNIVERSITY OF WASHINGTON (US) 1996-02-06 — — US disclosed
EP-0578774-A4 MONOCLONAL ANTIBODIES TO STEM CELL FACTOR RECEPTORS UNIV WASHINGTON (US) 1995-11-15 — — EP disclosed
EP-0307186-B1 Anti-ganglioside GD1a monoclonal antibody MZ, MZ-producing cells and MZ-containing reagent MITSUI TOATSU CHEMICALS (JP) 1994-06-22 — — EP disclosed
EP-0578774-A1 MONOCLONAL ANTIBODIES TO STEM CELL FACTOR RECEPTORS THE BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) 1994-01-19 — — EP disclosed
EP-0540314-A1 Monoclonal antibodies to polyacrylate polymers NALCO CHEMICAL COMPANY (US) 1993-05-05 — — EP disclosed
EP-0535347-A2 Monoclonal antibodies to sulfonated polymers NALCO CHEMICAL COMPANY (US) 1993-04-07 — — EP disclosed
US-5192662-A Screening for cancer cells MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-09 — — US disclosed
WO-1992017505-A1 MONOCLONAL ANTIBODIES TO STEM CELL FACTOR RECEPTORS BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) 1992-10-15 — — WO disclosed
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