Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057653 | 0.79 | DRD2 (0.61) | DHCR7ALDH1A1KDM4ESIGMAR1NPSR1 | |
| SCHEMBL3055295 | 0.78 | DHCR7 (0.58) | DHCR7ALDH1A1KDM4ESIGMAR1DRD2 | |
| SCHEMBL3050133 | 0.71 | DHCR7 (0.55) | DHCR7ALDH1A1KDM4ESIGMAR1DRD2 | |
| SCHEMBL3052036 | 0.68 | DHCR7 (0.80) | DHCR7ALDH1A1KDM4ESIGMAR1NPSR1 | |
| SCHEMBL3055394 | 0.68 | DHCR7 (0.54) | DHCR7ALDH1A1KDM4ESIGMAR1NPSR1 | |
| SCHEMBL3058753 | 0.67 | DHCR7 (0.53) | DHCR7ALDH1A1KDM4ESIGMAR1DRD2 | |
| SCHEMBL3061603 | 0.67 | CMA1 (0.52) | DHCR7ALDH1A1KDM4EDRD2DRD3 | |
| SCHEMBL3054533 | 0.67 | DHCR7 (0.70) | DHCR7ALDH1A1KDM4ESIGMAR1NPSR1 | |
| SCHEMBL3052820 | 0.66 | ROCK2 (0.55) | DHCR7DRD2DRD3ACHEMEN1 | |
| SCHEMBL3057093 | 0.65 | HCRTR1 (0.54) | SIGMAR1DRD2DRD1DRD3HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | DHCR7 421/4885ALDH1A1 1517/4885KDM4E 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.