SCHEMBL30528014

SCHEMBL30528014

CC(C)OC(=O)C[C@H](OC(=O)/C=C/C=C/c1ccccc1)C(=O)OC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B10 O60218 2/20 0.41
AKR1B1 P15121 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CYP1A2 P05177 2/20 0.40
TSHR P16473 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25853442 0.85 RAB9A (0.45) CYP1A2TSHRHDAC3HDAC4HDAC1
SCHEMBL25853430 0.84 HDAC3 (0.44) CYP1A2HDAC3HDAC4HDAC1HDAC7
SCHEMBL25853432 0.84 HDAC3 (0.44) CYP1A2HDAC3HDAC4HDAC1HDAC7
SCHEMBL15428801 0.83 CA12 (0.57) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL25299710 0.77 MMP1 (0.47) AKR1B1CYP1A2HDAC3HDAC4HDAC1
SCHEMBL5082817 0.77 KMT2A (0.54) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL25299709 0.77 MMP1 (0.47) AKR1B1CYP1A2HDAC3HDAC4HDAC1
SCHEMBL5082816 0.77 KMT2A (0.54) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL14356149 0.75 MEN1 (0.49) AKR1B10AKR1B1CA12CA1CA2
SCHEMBL15163756 0.75 MEN1 (0.49) AKR1B10AKR1B1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131362-A1 PHENYLPROPANOID DERIVATIVES USTAV EXPERIMENTALNI BOTANIKY AV ČR, V. V. I. (CZ) 2023-07-13 WO disclosed