Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | GAA | P10253 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | GLA | P06280 | 5/20 | 0.68 |
| ▸ | CASP1 | P29466 | 2/20 | 0.68 |
| ▸ | CASP7 | P55210 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993105 | 0.87 | KDM4E (0.73) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL27079801 | 0.86 | KDM4E (0.79) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL29749623 | 0.86 | MAOA (0.72) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL31550886 | 0.84 | KDM4E (0.50) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL12988158 | 0.82 | KDM4E (0.79) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL6991771 | 0.81 | KDM4E (0.62) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL12987943 | 0.81 | KDM4E (0.65) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL11066632 | 0.80 | KDM4E (0.61) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL11384270 | 0.78 | SRD5A1 (0.67) | KDM4EGAAALDH1A1MAPTKMT2A | |
| SCHEMBL7228410 | 0.76 | MAPT (0.56) | KDM4EGAAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012137224-A1 | COUMARIN COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | UNIVERSITY OF DELHI (IN) | 2012-10-11 | — | — | WO | claimed |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-01-10 | — | — | US | claimed |
| CN-110590575-B | Dye intermediate N-ethyl-N-gamma-hydroxy N-propyl m-toluidine and preparation method of esterification product thereof | 绍兴君泰纺织科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110590575-A | Dye intermediate N-ethyl-N-gamma-hydroxy N-propyl m-toluidine and preparation method of esterification product thereof | 绍兴君泰纺织科技有限公司 | 2019-12-20 | — | — | CN | disclosed |
| US-9775871-B2 | Herbal compositions and methods for treating hepatic disorders | SABELL CORPORATION (CA) | 2017-10-03 | — | — | US | disclosed |
| EP-2205255-B1 | HERBAL COMPOSITIONS AND METHODS FOR TREATING HEPATITIC DISORDERS | SABELL CORP (CA) | 2015-06-10 | — | — | EP | disclosed |
| US-8962244-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2015-02-24 | — | — | US | disclosed |
| US-8962244-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2013-08-22 | — | — | US | disclosed |
| EP-2001463-B1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2013-07-03 | — | — | EP | disclosed |
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-17 | — | — | US | disclosed |
| WO-2010151797-A2 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20100260874-A1 | HERBAL COMPOSITIONS AND METHODS FOR TREATING HEPATIC DISORDERS | CORAL, JOSE GONZALO CABANILLAS (PE) | 2010-10-14 | — | — | US | disclosed |
| EP-2205255-A1 | HERBAL COMPOSITIONS AND METHODS FOR TREATING HEPATITIC DISORDERS | Sabell Corporation (CA) | 2010-07-14 | — | — | EP | disclosed |
| CN-101437510-A | A pharmaceutical composition useful as acetyl cholinesterase inhibitors | COUNCIL SCIENT IND RES (IN) | 2009-05-20 | — | — | CN | disclosed |
| WO-2009043176-A1 | HERBAL COMPOSITIONS AND METHODS FOR TREATING HEPATIC DISORDERS | SABELL CORPORATION (CA) | 2009-04-09 | — | — | WO | disclosed |
| EP-2001463-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | Council of Scientific and Industrial Research (IN) | 2008-12-17 | — | — | EP | disclosed |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-01-10 | — | — | US | disclosed |
| WO-2007107846-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | KDM4E 3175/4885GAA 3022/4885ALDH1A1 3135/4885 |
| US-20080009544-A1 | Pharmaceutical Composition Useful as Acetylcholinesterase Inhibitors | ACHE, BCHE, CHRNB1 | KDM4E 1482/4885GAA 489/4885ALDH1A1 1025/4885 |
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | KDM4E 3175/4885GAA 3022/4885ALDH1A1 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.