Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284621 | 1.00 | LPL (0.43) | LPLLIPGDGAT1CA1CA2 | |
| SCHEMBL31212547 | 0.84 | DGAT1 (0.44) | LPLLIPGDGAT1ESR2F11 | |
| SCHEMBL3514966 | 0.84 | DGAT1 (0.44) | LPLLIPGDGAT1ESR2F11 | |
| SCHEMBL15805950 | 0.82 | GBA1 (0.47) | LPLLIPGDGAT1CA1CA2 | |
| SCHEMBL4553845 | 0.82 | DGAT1 (0.45) | LPLLIPGDGAT1CA1CA2 | |
| SCHEMBL29855985 | 0.82 | DGAT1 (0.45) | LPLLIPGDGAT1CA1CA2 | |
| SCHEMBL2601603 | 0.80 | LPL (0.49) | LPLLIPGDGAT1 | |
| SCHEMBL31212544 | 0.79 | LPL (0.47) | LPLLIPGDGAT1ESR2F11 | |
| SCHEMBL15941165 | 0.79 | DGAT1 (0.42) | LPLLIPGDGAT1CA1CA2 | |
| SCHEMBL31081894 | 0.78 | DGAT1 (0.43) | LPLLIPGDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472956-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | Bristol-Myers Squibb Company (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023147531-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |