Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.41 |
| ▸ | LPL | P06858 | 3/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553845 | 1.00 | DGAT1 (0.45) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL17421064 | 0.85 | DGAT1 (0.51) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL3792124 | 0.84 | DGAT1 (0.40) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL2182096 | 0.82 | DGAT1 (0.48) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL4165231 | 0.82 | SNCA (0.32) | DGAT1USP30 | |
| SCHEMBL29827999 | 0.82 | DGAT1 (0.48) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL4303492 | 0.82 | LIPG (0.36) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL1181140 | 0.82 | DGAT1 (0.48) | DGAT1LIPGLPLP4HBPDGFRB | |
| SCHEMBL1284621 | 0.82 | LPL (0.43) | DGAT1LIPGLPLF11CA1 | |
| SCHEMBL30529973 | 0.82 | LPL (0.43) | DGAT1LIPGLPLF11CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166916-A1 | SUBSTITUTED HETEROARYL DERIVATIVE, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2022-08-11 | — | — | WO | disclosed |