Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MITF | O75030 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380438 | 0.95 | HPGDS (0.64) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL4458404 | 0.83 | HPGDS (0.79) | MEN1KMT2AHPGDSALDH1A1GAA | |
| SCHEMBL29181717 | 0.83 | LMNA (0.62) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL10768107 | 0.81 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL10763115 | 0.81 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL10763104 | 0.81 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL7785221 | 0.80 | ALDH1A1 (0.64) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL7591232 | 0.80 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL4028148 | 0.80 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL4028151 | 0.80 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943199-B | Method for synthesizing amide compound by using nitrile and diaryl methane as raw materials | 浙江工业大学 | 2023-09-22 | — | — | CN | disclosed |