Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.44 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.44 |
| ▸ | NPY2R | P49146 | 6/20 | 0.44 |
| ▸ | NPY4R | P50391 | 6/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.44 |
| ▸ | NPY1R | P25929 | 4/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30733270 | 0.87 | RAMP3 (0.52) | NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30906441 | 0.85 | NPY2R (0.56) | NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30400638 | 0.85 | NTSR1 (0.57) | NTSR1NTSR2 | |
| SCHEMBL30400286 | 0.85 | NTSR1 (0.53) | NTSR1NTSR2NPY2RNPY4RNPY5R | |
| SCHEMBL30974285 | 0.83 | CAPN1 (0.45) | OPRD1OPRM1NPY2RNPY4RNPY5R | |
| SCHEMBL29695402 | 0.83 | NPY2R (0.46) | OPRD1OPRM1NPY2RNPY4RNPY5R | |
| SCHEMBL30973966 | 0.82 | CAPN1 (0.46) | OPRD1OPRM1BDKRB2 | |
| SCHEMBL38662669 | 0.82 | OPRD1 (0.47) | OPRD1NTSR1NTSR2NPY2RNPY4R | |
| SCHEMBL30930181 | 0.82 | OPRM1 (0.43) | OPRD1OPRM1NPY2RNPY4RNPY5R | |
| SCHEMBL38660296 | 0.81 | OPRM1 (0.53) | OPRD1OPRM1NTSR1NTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154906-A1 | COMBINATION THERAPY WITH SEMAPHORIN-4D BLOCKADE AND HTT-LOWERING AGENT FOR TREATMENT OF HUNTINGTON'S DISEASE | VACCINEX, INC. (US) | 2023-08-17 | — | — | WO | disclosed |