Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 1/20 | 0.66 |
| ▸ | NR1H2 | P55055 | 15/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLA1 | P09884 | 2/20 | 0.54 |
| ▸ | SOD1 | P00441 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311810 | 0.80 | NR1H2 (0.64) | NR1H2NR1H3POLA1SOD1 | |
| SCHEMBL6311814 | 0.80 | NR1H2 (0.64) | NR1H2NR1H3POLA1SOD1 | |
| Podocaric Acid SCHEMBL31181390 | 0.80 | NR1H2 (0.80) | KARS1NR1H2NR1H3POLA1SOD1 | |
| Podocaric Acid SCHEMBL32474685 | 0.80 | NR1H2 (0.80) | KARS1NR1H2NR1H3POLA1SOD1 | |
| Podocaric Acid SCHEMBL6311820 | 0.80 | NR1H2 (0.80) | KARS1NR1H2NR1H3POLA1SOD1 | |
| Podocaric Acid SCHEMBL14389445 | 0.80 | NR1H2 (0.80) | KARS1NR1H2NR1H3POLA1SOD1 | |
| Podocaric Acid SCHEMBL160062 | 0.80 | NR1H2 (0.80) | KARS1NR1H2NR1H3POLA1SOD1 | |
| Podocaric Acid SCHEMBL6312979 | 0.79 | NR1H2 (0.78) | KARS1NR1H2NR1H3POLA1SOD1 | |
| SCHEMBL20561234 | 0.79 | NR1H2 (0.76) | NR1H2NR1H3CYP3A4SOD1 | |
| SCHEMBL2993726 | 0.79 | NR1H2 (0.76) | NR1H2NR1H3CYP3A4SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115154466-B | Application of 2-aryl-1, 3-dihydrobenzimidazole derivative in preparation of medicine for treating diabetic nephropathy | 南方医科大学南方医院 | 2023-08-15 | — | — | CN | disclosed |