Podocaric Acid

Podocaric Acid

SCHEMBL160062

C[C@]1(C(=O)O)CCC[C@]2(C)c3cc(O)ccc3CC[C@@H]12

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 11/20 0.80
NR1H3 Q13133 11/20 0.80
POLA1 P09884 4/20 0.72
PDE4D Q08499 1/20 0.66
SOD1 P00441 1/20 0.64
RXRA P19793 1/20 0.64
CCNE1 P24864 1/20 0.64
CDK2 P24941 1/20 0.64
RXRB P28702 1/20 0.64
RXRG P48443 1/20 0.64
KARS1 Q15046 1/20 0.64
POLB P06746 1/20 0.63
APEX1 P27695 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Podocaric Acid SCHEMBL31181390 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL32474685 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL14389445 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL6311820 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL6312979 0.99 NR1H2 (0.78) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL14696167 0.91 SOD1 (0.77) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL15588775 0.91 SOD1 (0.77) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL7024094 0.91 SOD1 (0.77) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL2993726 0.89 NR1H2 (0.76) NR1H2NR1H3SOD1
SCHEMBL20561234 0.89 NR1H2 (0.76) NR1H2NR1H3SOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 968 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2025083496-A1 COMPOSITIONS FOR SEBUM CONTROL Dyson Operations PTE. LTD. (SG) 2025-04-24 WO claimed
WO-2025071908-A1 MALEATED FATTY IMIDAZOLINE DERIVATIVES FOR CORROSION INHIBITORS CHAMPIONX LLC (US) 2025-04-03 WO claimed
US-20250109503-A1 MALEATED FATTY IMIDAZOLINE DERIVATIVES FOR CORROSION INHIBITORS CHAMPIONX LLC (US) 2025-04-03 US claimed
US-20250099553-A1 COMPOSITION AND METHODS FOR MODULATION OF ELOVL2 YOUHEALTH BIOTECH, LIMITED (KY) 2025-03-27 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-20220409551-A1 COMPOSITION COMPRISING POLAR LIPIDS AND METHOD OF MAKING SAME Vaxa Technologies Ltd. (IL) 2022-12-29 US claimed
EP-4101835-A1 18F-SUBSTITUTED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Blanchette Rockefeller Neurosciences Institute (US) 2022-12-14 EP claimed
US-20220151973-A1 HALOGENATED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Synaptogenix, Inc. (US) 2022-05-19 US claimed
EP-3986387-A1 COMPOSITION COMPRISING POLAR LIPIDS AND METHOD OF MAKING SAME Vaxa Technologies Ltd. (IL) 2022-04-27 EP claimed
WO-2014043625-A1 THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME BIND THERAPEUTICS, INC. (US) 2014-03-20 WO claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
US-20110250183-A1 Combination Therapy for Treatment of Patients with Neurological Disorders and Cerebral Infarction MOLEAC PTE. LTD. (SG) 2011-10-13 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
CN-1989093-A Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives EASTMAN KODAK CO (US) 2007-06-27 CN claimed
US-7214834-B2 Process for preparing enantiomerically pure 1,1′-spirobiindane-6,6′-diol derivatives EASTMAN KODAK COMPANY (US) 2007-05-08 US claimed
EP-1768943-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 1,1'-SPIROBIINDANE-6,6'-DIOL DERIVATIVES EASTMAN KODAK COMPANY (US) 2007-04-04 EP claimed
WO-2006019663-A1 PROCESS FOR PREPARING ENANTIOMERICALLY PURE 1,1'-SPIROBIINDANE-6,6'-DIOL DERIVATIVES EASTMAN KODAK COMPANY (US) 2006-02-23 WO claimed
US-20060020150-A1 Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives EASTMAN KODAK COMPANY 2006-01-26 US claimed
US-4039334-A ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020150-A1 Process for preparing enantiomerically pure 1,1'-spirobiindane-6,6'-diol derivatives HSD11B1, PKD1, REN NR1H2 126/4885NR1H3 129/4885POLA1 952/4885
US-20220409551-A1 COMPOSITION COMPRISING POLAR LIPIDS AND METHOD OF MAKING SAME PHOSPHO1, CNR2, ELOVL3 NR1H2 69/4885NR1H3 39/4885POLA1 2826/4885
US-20250109503-A1 MALEATED FATTY IMIDAZOLINE DERIVATIVES FOR CORROSION INHIBITORS FASN, FFAR1, IGF1R NR1H2 1708/4885NR1H3 1384/4885POLA1 3139/4885
US-20220151973-A1 HALOGENATED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES PRKCH, PRKCA, PRKCD NR1H2 214/4885NR1H3 163/4885POLA1 2693/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS NR1H2 4830/4885NR1H3 4854/4885POLA1 2848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.