Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.76 |
| ▸ | NR1H3 | Q13133 | 18/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | SOD1 | P00441 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20561234 | 1.00 | NR1H2 (0.76) | NR1H2NR1H3LMNACYP3A4SOD1 | |
| SCHEMBL2994458 | 0.91 | SOD1 (0.75) | NR1H2NR1H3LMNACYP3A4SOD1 | |
| Podocaric Acid SCHEMBL6311820 | 0.89 | NR1H2 (0.80) | NR1H2NR1H3SOD1 | |
| Podocaric Acid SCHEMBL32474685 | 0.89 | NR1H2 (0.80) | NR1H2NR1H3SOD1 | |
| Podocaric Acid SCHEMBL14389445 | 0.89 | NR1H2 (0.80) | NR1H2NR1H3SOD1 | |
| Podocaric Acid SCHEMBL31181390 | 0.89 | NR1H2 (0.80) | NR1H2NR1H3SOD1 | |
| Podocaric Acid SCHEMBL160062 | 0.89 | NR1H2 (0.80) | NR1H2NR1H3SOD1 | |
| SCHEMBL24591878 | 0.88 | LMNA (0.65) | NR1H2NR1H3LMNACYP3A4SOD1 | |
| SCHEMBL2986350 | 0.88 | LMNA (0.65) | NR1H2NR1H3LMNACYP3A4SOD1 | |
| Podocaric Acid SCHEMBL6312979 | 0.88 | NR1H2 (0.78) | NR1H2NR1H3SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1604212-A2 | MODULATORS OF THE G PROTEIN-COUPLED FORMYL PEPTIDE RECEPTOR-LIKE 2 AND THEIR THERAPEUTIC USE AGAINST CELL DEATH-RELATED DISORDERS | Arena Pharmaceuticals, Inc. (US) | 2005-12-14 | — | — | EP | claimed |
| WO-2004083867-A2 | MODULATORS OF G PROTEIN-COUPLED FORMYL PEPTIDE RECEPTOR-LIKE 2 AND THEIR THERAPEUTIC USE AGAINST CELL DEATH-RELATED DISORDERS | ARENA PHARMACEUTICALS INC. (US) | 2004-09-30 | — | — | WO | claimed |
| US-20250270163-A1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF | REGENERON PHARMA (US) | 2025-08-28 | — | — | US | disclosed |
| US-7776558-B2 | Human G protein-coupled receptor and modulators thereof for the treatment of cell death-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776558-B2 | Human G protein-coupled receptor and modulators thereof for the treatment of cell death-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20080125491-A1 | Human G Protein-Coupled Receptor and Modulators Thereof for the Treatment of Cell Death-Related Disorders | ARENA PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080125491-A1 | Human G Protein-Coupled Receptor and Modulators Thereof for the Treatment of Cell Death-Related Disorders | ARENA PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125491-A1 | Human G Protein-Coupled Receptor and Modulators Thereof for the Treatment of Cell Death-Related Disorders | GPR65, GPR3, GPR52 | NR1H2 1032/4885NR1H3 1477/4885LMNA 1175/4885 |
| US-20250270163-A1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDES AND PROTEIN CONJUGATES THEREOF | NR1H4, NR1H3, OGFR | NR1H2 4/4885NR1H3 2/4885LMNA 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.