Podocaric Acid

Podocaric Acid

SCHEMBL31181390

CC1(C(=O)O)CCCC2(C)c3cc(O)ccc3CCC12

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 11/20 0.80
NR1H3 Q13133 11/20 0.80
POLA1 P09884 4/20 0.72
PDE4D Q08499 1/20 0.66
SOD1 P00441 1/20 0.64
RXRA P19793 1/20 0.64
CCNE1 P24864 1/20 0.64
CDK2 P24941 1/20 0.64
RXRB P28702 1/20 0.64
RXRG P48443 1/20 0.64
KARS1 Q15046 1/20 0.64
POLB P06746 1/20 0.63
APEX1 P27695 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Podocaric Acid SCHEMBL160062 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL32474685 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL14389445 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL6311820 1.00 NR1H2 (0.80) NR1H2NR1H3POLA1PDE4DSOD1
Podocaric Acid SCHEMBL6312979 0.99 NR1H2 (0.78) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL14696167 0.91 SOD1 (0.77) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL15588775 0.91 SOD1 (0.77) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL7024094 0.91 SOD1 (0.77) NR1H2NR1H3POLA1PDE4DSOD1
SCHEMBL2993726 0.89 NR1H2 (0.76) NR1H2NR1H3SOD1
SCHEMBL20561234 0.89 NR1H2 (0.76) NR1H2NR1H3SOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023086465-A9 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2024-08-22 WO disclosed