Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534523 | 0.85 | P2RX4 (0.37) | LMNAALDH1A1GAANPSR1SMN1; SMN2 | |
| SCHEMBL30933611 | 0.85 | P2RX4 (0.37) | LMNAALDH1A1GAANPSR1P2RX4 | |
| SCHEMBL30933585 | 0.85 | AHR (0.32) | — | |
| SCHEMBL30933597 | 0.81 | HSP90AA1 (0.37) | ALDH1A1NPSR1 | |
| SCHEMBL30933583 | 0.81 | MGLL (0.38) | LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31268391 | 0.79 | MGLL (0.40) | ALDH1A1 | |
| SCHEMBL31268392 | 0.78 | MEN1 (0.38) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30534505 | 0.78 | MGLL (0.41) | — | |
| SCHEMBL30933613 | 0.77 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30534490 | 0.77 | MGLL (0.36) | LMNAALDH1A1GAAHTTP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-B | 4-Aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-118165009-A | 6-Aryl-1, 4-benzoxazine-imidazoline (thio) ketone compound and preparation method and application thereof | 湖南科技大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-116462686-A | 4-aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2023-07-21 | — | — | CN | disclosed |