Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933611 | 0.82 | P2RX4 (0.37) | MAPTALDH1A1LMNAHTR3EHTR3B | |
| SCHEMBL27317176 | 0.81 | LMNA (0.32) | ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL30534544 | 0.81 | LMNA (0.32) | ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL30933597 | 0.81 | HSP90AA1 (0.37) | MGLLMAPTALDH1A1ADRB1IDO1 | |
| SCHEMBL31268391 | 0.79 | MGLL (0.40) | MGLLMAPTALDH1A1ADRB1FGFR1 | |
| SCHEMBL30534505 | 0.78 | MGLL (0.41) | MGLLMAPTTP53CYP1A2SIGMAR1 | |
| SCHEMBL31268392 | 0.75 | MEN1 (0.38) | MAPTALDH1A1SMN1; SMN2ADRB1THRB | |
| SCHEMBL30534490 | 0.75 | MGLL (0.36) | MGLLMAPTALDH1A1LMNATP53 | |
| SCHEMBL21710825 | 0.73 | MEN1 (0.39) | MGLLALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL30933585 | 0.72 | AHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462686-B | 4-Aryl (methyl) group-1, 4-benzoxazine imidazoline compound and preparation method and application thereof | 湖南科技大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-118165009-A | 6-Aryl-1, 4-benzoxazine-imidazoline (thio) ketone compound and preparation method and application thereof | 湖南科技大学 | 2024-06-11 | — | — | CN | disclosed |