SCHEMBL305355

SCHEMBL305355

O=C(O)NCc1nc2ccccc2[nH]1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.64
RAB9A P51151 2/20 0.64
KMT2A Q03164 1/20 0.64
SMN1; SMN2 Q16637 4/20 0.63
TSHR P16473 2/20 0.63
MAPK10 P53779 2/20 0.63
CHRM1 P11229 1/20 0.60
PKM P14618 1/20 0.59
MAPT P10636 2/20 0.59
HTT P42858 2/20 0.58
GAA P10253 3/20 0.58
LMNA P02545 1/20 0.57
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HSD17B10 Q99714 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27826900 0.98 POLB (0.63) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL7080320 0.86 MAPT (0.73) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL12851299 0.86 HTT (0.74) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL3915446 0.86 POLB (0.63) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL7977173 0.86 POLB (0.63) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL1386409 0.84 LMNA (0.62) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL10454789 0.84 HTT (0.76) SMN1; SMN2TSHRCHRM1MAPTHTT
SCHEMBL1386414 0.84 LMNA (0.62) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL12201106 0.83 SMN1; SMN2 (0.75) POLBRAB9AKMT2ASMN1; SMN2TSHR
SCHEMBL6908821 0.83 SMN1; SMN2 (0.63) POLBRAB9AKMT2ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118160717-A Prochloraz-containing bactericidal composition and preparation method and application thereof 北京市农林科学院 2024-06-11 CN claimed
CN-117356358-A Pleurotus geesteranus culture medium using eucommia ulmoides branches as matrix and preparation method thereof 慈利县九九农业开发有限公司 2024-01-09 CN claimed
EP-0513409-B1 Use of a microbicide agent for making concrete shingles RIEDEL DE HAEN AG (DE) 1996-07-24 EP claimed
EP-0513409-A1 Use of a microbicide agent for making concrete shingles RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1992-11-19 EP claimed
EP-0016857-B1 MICROBICIDAL AGENT AND APPLICATION THEREOF BAYER AG (DE) 1982-06-09 EP claimed
EP-0051198-A1 Method for the preparation of 2-halo-3-sulfonyl-acrylonitriles and their use BAYER AG (DE) 1982-05-12 EP claimed
EP-0016857-A1 Microbicidal agent and application thereof BAYER AG (DE) 1980-10-15 EP claimed
JP-61129102-A None JP disclosed
US-12089593-B2 Compositions and methods for treating and preventing dust mite infestation DANSTAR FERMENT AG (CH) 2024-09-17 US disclosed
CN-118160717-A Prochloraz-containing bactericidal composition and preparation method and application thereof 北京市农林科学院 2024-06-11 CN disclosed
CN-118160717-A Prochloraz-containing bactericidal composition and preparation method and application thereof 北京市农林科学院 2024-06-11 CN disclosed
CN-117356358-A Pleurotus geesteranus culture medium using eucommia ulmoides branches as matrix and preparation method thereof 慈利县九九农业开发有限公司 2024-01-09 CN disclosed
US-20210054169-A1 COMPOSITION AND MOLDED BODY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-02-25 US disclosed
EP-0047850-A2 Use of 4-nitroso-pyrazoles in microbiocidal compositions BAYER AG (DE) 1982-03-24 EP disclosed
EP-0047451-A2 Fluoro and chloromethylthioamino-benzamides, preparation and use thereof BAYER AG (DE) 1982-03-17 EP disclosed
EP-0045907-A1 Use of N-alkyl-2,3-dichloromaleine imides as microbicides BAYER AG (DE) 1982-02-17 EP disclosed
EP-0000892-B1 ORGANOPOLYSILOXANE COMPOSITIONS WITH MICROBICIDAL ACTIVITY THAT CAN BE STORED IN THE ABSENCE OF WATER BAYER AG (DE) 1981-03-18 EP disclosed
EP-0016857-A1 Microbicidal agent and application thereof BAYER AG (DE) 1980-10-15 EP disclosed
US-4228065-A Microbiocidal organopolysiloxane molding compositions BAYER AKTIENGESELLSCHAFT (DE) 1980-10-14 US disclosed
EP-0000892-A1 Organopolysiloxane compositions with microbicidal activity that can be stored in the absence of water BAYER AG (DE) 1979-03-07 EP disclosed