Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25351911 | 1.00 | KAT6A (0.51) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL30535678 | 0.90 | KAT6A (0.51) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL25353685 | 0.90 | KAT6A (0.51) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL31610063 | 0.89 | DHX9 (0.57) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL25431434 | 0.89 | DHX9 (0.57) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL25350503 | 0.83 | HTT (0.43) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL30535005 | 0.83 | HTT (0.43) | KAT6AMEN1KMT2ADHX9HTT | |
| SCHEMBL25352121 | 0.82 | MEN1 (0.41) | MEN1KMT2ADHX9HTTALDH1A1 | |
| SCHEMBL25430854 | 0.82 | DHX9 (0.42) | MEN1KMT2ADHX9HTTALDH1A1 | |
| SCHEMBL30535450 | 0.82 | DHX9 (0.42) | MEN1KMT2ADHX9HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4479138-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | Accent Therapeutics, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023154519-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |