Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 8/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456870 | 1.00 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1747900 | 0.74 | — | — | |
| SCHEMBL1747901 | 0.74 | UHRF1 (0.37) | — | |
| SCHEMBL30538678 | 0.74 | UHRF1 (0.37) | — | |
| SCHEMBL1490653 | 0.67 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL2624085 | 0.67 | TSHR (0.49) | MAPTCHEK1TSHRHTTKMT2A | |
| SCHEMBL2707307 | 0.67 | NSD2 (0.40) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1140881 | 0.67 | ACHE (0.41) | TSHRKMT2A | |
| SCHEMBL6244651 | 0.66 | ACHE (0.40) | TSHRKMT2A | |
| SCHEMBL728744 | 0.66 | GABRA1 (0.38) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402518-B | Imidazo [4,5-c ] ring compounds containing substituted guanidine groups | 3M创新有限公司 | 2023-08-22 | — | — | CN | disclosed |