Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.47 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153537 | 1.00 | TSHR (0.68) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL31179981 | 0.91 | MAOB (0.58) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL1100246 | 0.91 | MAOB (0.58) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL8580005 | 0.89 | TSHR (0.58) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL7195314 | 0.89 | TSHR (0.58) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL9798371 | 0.88 | LTA4H (0.54) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL476378 | 0.87 | ALDH1A1 (0.66) | TSHRMAPK1MAOBMAPTADORA2A | |
| SCHEMBL30098473 | 0.87 | MAOB (0.63) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL4703990 | 0.87 | MAOB (0.63) | TSHRMAPK1MAOBMAPTPOLB | |
| SCHEMBL29360696 | 0.86 | MAOB (0.56) | TSHRMAPK1MAOBMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631573-A2 | TEAD INHIBITORS | Orion Corporation (FI) | 2025-10-15 | — | — | EP | disclosed |
| EP-4323338-B1 | TEAD INHIBITORS | ORION CORP (FI) | 2025-10-08 | — | — | EP | disclosed |
| CN-116490201-A | Inhibitors of YAP/TAZ-TEAD tumor proteins, their synthesis and use | 布里奇恩生物科学公司 | 2023-07-25 | — | — | CN | disclosed |