SCHEMBL476378

SCHEMBL476378

Nc1ccc(Oc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
MAPT P10636 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
MITF O75030 1/20 0.66
GAA P10253 1/20 0.66
GFER P55789 1/20 0.66
NLRP1 Q9C000 1/20 0.66
NOD2 Q9HC29 1/20 0.66
MAOB P27338 3/20 0.58
TSHR P16473 2/20 0.55
MAPK1 P28482 2/20 0.55
MAOA P21397 1/20 0.53
LTA4H P09960 1/20 0.52
TTBK1 Q5TCY1 2/20 0.52
TTBK2 Q6IQ55 1/20 0.52
CYP3A4 P08684 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KIF11 P52732 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27579381 0.91 LTA4H (0.59) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL6153537 0.87 TSHR (0.68) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL30539120 0.87 TSHR (0.68) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9798371 0.87 LTA4H (0.54) ALDH1A1MAPTMAOBTSHRMAPK1
SCHEMBL29551212 0.86 ALDH1A1 (0.61) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL310455 0.86 ALDH1A1 (0.61) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9546526 0.85 L3MBTL1 (0.55) ALDH1A1SMN1; SMN2GAAMAOBTSHR
SCHEMBL8580005 0.84 TSHR (0.58) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL28621904 0.83 ALDH1A1 (0.58) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL8152515 0.83 ALDH1A1 (0.56) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3797991-B1 PREPREG AND PRODUCTION METHOD THEREFOR, SLIT TAPE PREPREG, CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-10-29 EP disclosed
US-12448510-B2 Prepreg, method for producing same, and slit tape prepreg TORAY INDUSTRIES, INC. (JP) 2025-10-21 US disclosed
EP-3995536-B1 PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-06-18 EP disclosed
EP-4565323-A1 AROMATIC COMPOUNDS FOR USE AS PROTEIN PHOSPHATASE 2A (PP2A) MODULATORS Rappta Therapeutics Oy (FI) 2025-06-11 EP disclosed
CN-119968358-A Protein phosphatase 2A (PP 2A) modulators and methods of use thereof 拉普他治疗公司 2025-05-09 CN disclosed
US-20240166798-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2024-05-23 US disclosed
WO-2024028808-A1 AROMATIC COMPOUNDS FOR USE AS PROTEIN PHOSPHATASE 2A (PP2A) MODULATORS RAPPTA THERAPEUTICS OY (FI) 2024-02-08 WO disclosed
EP-4314108-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2024-02-07 EP disclosed
US-20230357561-A1 PREPREG, METHOD FOR PRODUCING SAME, AND SLIT TAPE PREPREG TORAY INDUSTRIES, INC. (JP) 2023-11-09 US disclosed
US-11708487-B2 Prepreg, method for producing same, and slit tape prepreg TORAY INDUSTRIES, INC. (JP) 2023-07-25 US disclosed
EP-0231512-A1 Cyclic malonylphosphonic acid diamides, process for their preparation and their use for pestcontrol BAYER AG (DE) 1987-08-12 EP disclosed
EP-0216105-A1 Diazaphosphorines, process for their preparation and their use as pesticide BAYER AG (DE) 1987-04-01 EP disclosed
EP-0074074-B1 N-BENZOYL-N'-PHENOXYPHENYL UREAS, PREPARATION THEREOF AND USE THEREOF AS INSECTICIDES BASF Aktiengesellschaft (DE) 1985-12-27 EP disclosed
EP-0037925-B1 SUBSTITUTED PYRIDAZINONES, PROCESS FOR THEIR PREPARATION, HERBICIDES CONTAINING THEM AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1983-06-22 EP disclosed
EP-0074074-A2 N-benzoyl-N'-phenoxyphenyl ureas, preparation thereof and use thereof as insecticides BASF Aktiengesellschaft (DE) 1983-03-16 EP disclosed
US-4360672-A Substituted phenoxyphenyl pyridazones, their preparation, and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
EP-0037925-A1 Substituted pyridazinones, process for their preparation, herbicides containing them and their use as herbicides BASF Aktiengesellschaft (DE) 1981-10-21 EP disclosed
US-4279637-A Herbicidal N-substituted 4-imidazolin-2-ones VELSICOL CHEMICAL CORPORATION (US) 1981-07-21 US disclosed
US-4087272-A POSTEMERGENCE HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-02 US disclosed
US-3968228-A 4-Nitro-5-cyanoimidazoles as coccidiostats MERCK & CO., INC. (US) 1976-07-06 US disclosed