Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445235 | 1.00 | GABRA1 (0.56) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL1993247 | 0.89 | GABRA1 (0.67) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL6490095 | 0.86 | GABRA1 (0.70) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL6029933 | 0.85 | NR4A2 (0.57) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL1557626 | 0.84 | ALDH1A1 (0.47) | GABRA1GABRB2NR4A2MEN1LMNA | |
| SCHEMBL4801726 | 0.84 | NR4A2 (0.60) | NR4A2MAPT | |
| SCHEMBL1557688 | 0.83 | MAPT (0.64) | NR4A2MEN1LMNAMAPTKMT2A | |
| SCHEMBL1559282 | 0.81 | MEN1 (0.54) | GABRA1GABRB2NR4A2MEN1KMT2A | |
| SCHEMBL29790938 | 0.80 | GABRA1 (0.58) | GABRA1GABRB2GABRA3NR4A2LMNA | |
| SCHEMBL368012 | 0.80 | GABRA1 (0.58) | GABRA1GABRB2GABRA3NR4A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521387-B | NLRP3 modulators | 先天肿瘤免疫公司 | 2023-08-22 | — | — | CN | disclosed |