Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 6/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635312 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GAAERN1XDHSRC | |
| SCHEMBL30540234 | 0.82 | ERN1 (0.40) | ALDH1A1GAAERN1XDHSRC | |
| SCHEMBL26635154 | 0.82 | ERN1 (0.40) | ALDH1A1GAAERN1XDHSRC | |
| SCHEMBL30540195 | 0.81 | ERN1 (0.42) | ALDH1A1GAAERN1XDHSRC | |
| SCHEMBL26635306 | 0.81 | ERN1 (0.42) | ALDH1A1GAAERN1XDHSRC | |
| SCHEMBL8580981 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GAAERN1SRCPOLB | |
| SCHEMBL30540219 | 0.76 | NFKB1 (0.40) | ERN1XDHTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL26635334 | 0.76 | NFKB1 (0.40) | ERN1XDHTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL30540216 | 0.74 | ERN1 (0.34) | ALDH1A1ERN1XDHSRCHPGD | |
| SCHEMBL26635324 | 0.74 | ERN1 (0.34) | ALDH1A1ERN1XDHSRCHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |