Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 10/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | PIM1 | P11309 | 5/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.45 |
| ▸ | RET | P07949 | 3/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 3/20 | 0.45 |
| ▸ | FLT4 | P35916 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775205 | 0.85 | KDR (0.49) | KDRROCK2PIM1ROCK1CLK4 | |
| SCHEMBL30775209 | 0.82 | CNR2 (0.58) | CNR2KDR | |
| SCHEMBL30775367 | 0.81 | L3MBTL1 (0.52) | PIM1ROCK1CLK4DYRK1ACDK5 | |
| SCHEMBL30543359 | 0.81 | KDR (0.50) | KDRROCK2PIM1ROCK1MAP4K4 | |
| SCHEMBL30331758 | 0.75 | PARP10 (0.69) | KDRROCK2PIM1ROCK1CLK4 | |
| SCHEMBL19608227 | 0.74 | PIK3CD (0.64) | KDRROCK2PIM1ROCK1CLK4 | |
| SCHEMBL1333209 | 0.74 | KDR (0.57) | KDRROCK2PIM1ROCK1CLK4 | |
| SCHEMBL28223904 | 0.74 | PIK3CD (0.64) | KDRROCK2PIM1ROCK1CLK4 | |
| SCHEMBL30598685 | 0.72 | TBK1 (0.56) | PIK3CDPIK3CAPIK3CBMKNK2TBK1 | |
| SCHEMBL28241795 | 0.72 | OGA (0.50) | KDRCLK4DYRK1BPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496246-A | Isoindoline compound, preparation method, pharmaceutical composition and application | 中国药科大学 | 2023-07-28 | — | — | CN | claimed |
| CN-116496246-A | Isoindoline compound, preparation method, pharmaceutical composition and application | 中国药科大学 | 2023-07-28 | — | — | CN | disclosed |