Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.58 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222936 | 1.00 | ADRA2A (0.58) | ADRA2AMAP3K14TERTMAOBMAOA | |
| SCHEMBL29222702 | 0.84 | ADRA2A (0.58) | ADRA2A | |
| SCHEMBL5827525 | 0.84 | ADRA2A (0.41) | ADRA2AJAK2JAK3 | |
| SCHEMBL30543425 | 0.84 | ADRA2A (0.58) | ADRA2A | |
| SCHEMBL30543393 | 0.84 | ADRA2A (0.58) | ADRA2AMAOBMAOA | |
| SCHEMBL29222642 | 0.84 | ADRA2A (0.58) | ADRA2AMAOBMAOA | |
| SCHEMBL29222605 | 0.81 | PIK3CA (0.39) | ADRA2A | |
| SCHEMBL29222699 | 0.76 | ADRA2A (0.58) | ADRA2AMAP3K14MAOBMAOA | |
| SCHEMBL29222640 | 0.76 | ADRA2A (0.58) | ADRA2AJAK2JAK3 | |
| SCHEMBL6174442 | 0.75 | RAB9A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496261-A | 4- (1H) -imidazole derivative and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-07-28 | — | — | CN | disclosed |