Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL28036619 | 0.88 | LMNA (0.45) | LMNASIGMAR1CXCR4HTR6CHRM2 | |
| SCHEMBL247774 | 0.85 | ALDH1A1 (0.56) | SIGMAR1ALDH1A1HRH3CYP2A13 | |
| SCHEMBL10315553 | 0.83 | ALDH1A1 (0.59) | LMNAALDH1A1HRH3 | |
| SCHEMBL2925434 | 0.83 | LMNA (0.54) | LMNASIGMAR1CXCR4HTR6CHRM2 | |
| SCHEMBL11558241 | 0.83 | LMNA (0.62) | LMNASIGMAR1CXCR4HTR6CHRM2 | |
| SCHEMBL21416735 | 0.81 | LMNA (0.59) | LMNASIGMAR1CXCR4HTR6CHRM2 | |
| SCHEMBL24113849 | 0.81 | KDM4E (0.48) | LMNAHTR6ALDH1A1ADRA2C | |
| SCHEMBL22684197 | 0.81 | LMNA (0.44) | LMNASIGMAR1CXCR4CHRM2ALDH1A1 | |
| SCHEMBL249086 | 0.81 | CYP2A13 (0.61) | LMNACXCR4ALDH1A1MEN1KMT2A | |
| SCHEMBL29738173 | 0.81 | LMNA (0.51) | LMNASIGMAR1CXCR4ALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970123-B2 | CRYSTALLINE DIHYDROCHLORIDE HYDRATE SALT OF OMECAMTIV MECARBIL AND PROCESS FOR ITS PREPARATION | AMGEN INC (US) | 2025-12-10 | — | — | EP | claimed |
| EP-3925950-B1 | SYNTHESIS OF OMECAMTIV MECARBIL | AMGEN INC (US) | 2023-09-06 | — | — | EP | claimed |