Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543439 | 0.88 | LMNA (0.51) | LMNASLC6A4CYP1A2CHRM2OPRD1 | |
| Formic Acid Methyl Ester SCHEMBL28257897 | 0.81 | ACHE (0.44) | LMNASLC6A4CYP1A2CHRM2OPRD1 | |
| SCHEMBL247774 | 0.75 | ALDH1A1 (0.56) | CYP2D6SIGMAR1KDM4E | |
| SCHEMBL24113849 | 0.74 | KDM4E (0.48) | LMNAHTR6KDM4E | |
| SCHEMBL21416735 | 0.74 | LMNA (0.59) | LMNASLC6A4CYP1A2CHRM2OPRD1 | |
| SCHEMBL7859088 | 0.73 | ALDH1A1 (0.53) | LMNACYP2D6KDM4E | |
| SCHEMBL30477345 | 0.73 | ALDH1A1 (0.53) | LMNACYP2D6KDM4E | |
| SCHEMBL10315553 | 0.73 | ALDH1A1 (0.59) | LMNACYP2D6KDM4E | |
| SCHEMBL2925434 | 0.73 | LMNA (0.54) | LMNASLC6A4CYP1A2CHRM2OPRD1 | |
| SCHEMBL11558241 | 0.73 | LMNA (0.62) | LMNASLC6A4CYP1A2CHRM2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105120844-A | Heterocyclic compounds and uses thereof | AMGEN INC | 2015-12-02 | — | — | CN | disclosed |