SCHEMBL30543489

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC(=O)[C@@H](NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@@H](COC)NC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	5/20	0.42

▸	OPRD1	P41143	5/20	0.42

▸	OPRK1	P41145	5/20	0.42

▸	GLP1R	P43220	13/20	0.40

▸	PSEN1	P49768	2/20	0.39

▸	PSEN2	P49810	2/20	0.39

▸	APH1B	Q8WW43	2/20	0.39

▸	NCSTN	Q92542	2/20	0.39

▸	APH1A	Q96BI3	2/20	0.39

▸	PSENEN	Q9NZ42	2/20	0.39

▸	GCGR	P47871	1/20	0.39

▸	GIPR	P48546	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30543485	0.98	OPRM1 (0.43)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL30543477	0.94	OPRM1 (0.44)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL30543483	0.94	OPRM1 (0.45)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL30543487	0.94	OPRM1 (0.45)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL30543486	0.93	OPRM1 (0.46)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL38651875	0.92	OPRM1 (0.46)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL38651798	0.92	OPRM1 (0.46)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL30662558	0.92	OPRM1 (0.43)	OPRM1OPRD1OPRK1PSEN1PSEN2
SCHEMBL30543484	0.91	OPRM1 (0.44)	OPRM1OPRD1OPRK1GLP1RPSEN1
SCHEMBL30892071	0.91	OPRM1 (0.44)	OPRM1OPRD1OPRK1GLP1RPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230241178-A1	LONG ACTING GLP-1/GIP DUAL AGONISTS	SUN PHARMACEUTICAL IND LTD (IN)	2023-08-03	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230241178-A1	LONG ACTING GLP-1/GIP DUAL AGONISTS	GLP1R, GIPR, GPR119	OPRM1 1258/4885OPRD1 923/4885OPRK1 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.