Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340693 | 1.00 | GPR139 (0.38) | GPR139TP53MAPTAKR1C3EPHX2 | |
| SCHEMBL25955696 | 0.82 | GPR139 (0.38) | GPR139TP53 | |
| SCHEMBL30482521 | 0.75 | TP53 (0.45) | TP53MAPTAKR1C3TEAD1YAP1 | |
| SCHEMBL25377073 | 0.75 | TP53 (0.45) | TP53MAPTAKR1C3TEAD1YAP1 | |
| SCHEMBL20552265 | 0.73 | ABCG2 (0.45) | TP53MAPT | |
| SCHEMBL16579450 | 0.71 | GPR139 (0.44) | GPR139PDE10ASCN5AHTR1ADRD2 | |
| SCHEMBL25339701 | 0.70 | TEAD1 (0.40) | TP53MAPTAKR1C3EPHX2TEAD1 | |
| SCHEMBL30544052 | 0.70 | TEAD1 (0.40) | TP53MAPTAKR1C3EPHX2TEAD1 | |
| SCHEMBL20552848 | 0.70 | TAS2R14 (0.39) | MAPTEPHX2HDAC1TEAD1YAP1 | |
| SCHEMBL20552285 | 0.69 | ABCG2 (0.43) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |