Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.33 |
| ▸ | ITGAL | P20701 | 6/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | GPR142 | Q7Z601 | 6/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25955585 | 0.88 | GPR142 (0.34) | ITGB2ICAM1ITGALTRPV1PIK3CA | |
| SCHEMBL25955625 | 0.83 | PDE10A (0.35) | TRPV1PIK3CAGPR142CYP2D6CYP2C9 | |
| SCHEMBL25339990 | 0.78 | GPR142 (0.36) | ITGB2ICAM1ITGALTRPV1PIK3CA | |
| SCHEMBL30544079 | 0.78 | GPR142 (0.36) | ITGB2ICAM1ITGALTRPV1PIK3CA | |
| SCHEMBL25955304 | 0.74 | CYP1A2 (0.33) | CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL21780467 | 0.71 | KCNH2 (0.45) | TRPV1PIK3CAGPR142CYP2D6CYP2C9 | |
| SCHEMBL22563248 | 0.70 | TLR8 (0.36) | TRPV1PIK3CAGPR142CYP2D6CYP2C9 | |
| SCHEMBL25955286 | 0.69 | TGFBR1 (0.32) | TRPV1 | |
| SCHEMBL21780488 | 0.68 | ROCK2 (0.36) | TRPV1PIK3CAGPR142CYP2D6CYP2C9 | |
| SCHEMBL30544122 | 0.67 | TRPV1 (0.37) | TRPV1CYP2D6CYP2C9CYP3A4SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |