SCHEMBL305462

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL476793	0.86	CYP1A2 (0.51)	CYP1A2CYP17A1MKNK1MKNK2SCN9A
	Hydrochloric Acid SCHEMBL304059	0.85	CYP1A2 (0.50)	CYP1A2CYP17A1MKNK1MKNK2SCN9A
	SCHEMBL303982	0.83	CYP17A1 (0.56)	CYP1A2CYP17A1MKNK1MKNK2CCR1
	SCHEMBL25257558	0.81	XDH (0.53)	CYP1A2CYP17A1MKNK1MKNK2CCR1
	SCHEMBL30491768	0.81	XDH (0.53)	CYP1A2CYP17A1MKNK1MKNK2CCR1
	SCHEMBL30491699	0.78	XDH (0.53)	CYP1A2CYP17A1MKNK1MKNK2LMNA
	SCHEMBL304096	0.78	XDH (0.53)	CYP1A2CYP17A1MKNK1MKNK2LMNA
	SCHEMBL4573821	0.76	MAPK14 (0.50)	CYP1A2CYP17A1MKNK1MKNK2CCR1
	Hydrochloric Acid SCHEMBL5551165	0.76	MKNK1 (0.42)	CYP1A2CYP17A1MKNK1MKNK2CCR1
	SCHEMBL4572945	0.75	MKNK1 (0.47)	CYP1A2CYP17A1MKNK1MKNK2CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.