Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594876 | 0.82 | KMT2A (0.54) | ACLYKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5279632 | 0.80 | ALDH1A1 (0.79) | ACLYKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30547669 | 0.80 | ALDH1A1 (0.53) | ACLYALDH1A1HSD17B10KDM1A | |
| SCHEMBL30547588 | 0.80 | ALDH1A1 (0.53) | ACLYKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23141311 | 0.79 | ACLY (0.48) | ACLYKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24268171 | 0.77 | ACLY (0.46) | ACLYKDM1APTPN1 | |
| SCHEMBL23877534 | 0.76 | ACLY (0.46) | ACLYKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5594924 | 0.76 | MAPT (0.57) | ACLYALDH1A1KMT2AMEN1GAA | |
| SCHEMBL5667543 | 0.75 | CCR2 (0.66) | ACLYALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL26189523 | 0.75 | ACLY (0.45) | ACLYKDM1AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3796975-B1 | SULFONYLAMINOBENZAMIDE DERIVATIVES | ORSOBIO INC (US) | 2023-08-30 | — | — | EP | disclosed |