Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.53 |
| ▸ | SKP1 | P63208 | 2/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265687 | 1.00 | CKS1B (0.53) | CKS1BSKP1SKP2PRMT5ACHE | |
| SCHEMBL24265726 | 0.79 | MAP4K4 (0.52) | CKS1BSKP1SKP2PRMT5ACHE | |
| SCHEMBL30548148 | 0.79 | MAP4K4 (0.52) | CKS1BSKP1SKP2PRMT5ACHE | |
| SCHEMBL24265827 | 0.78 | GPR119 (0.46) | MAP4K4GPR119 | |
| SCHEMBL30548162 | 0.78 | GPR119 (0.46) | MAP4K4GPR119 | |
| SCHEMBL29574092 | 0.78 | GPR119 (0.46) | MAP4K4GPR119 | |
| SCHEMBL24265694 | 0.75 | HTR3A (0.49) | MAPT | |
| SCHEMBL4055019 | 0.75 | PDE10A (0.64) | CKS1BSKP1SKP2MAP4K4PDE10A | |
| SCHEMBL25177953 | 0.75 | GPR119 (0.58) | CKS1BSKP1SKP2PRMT5ACHE | |
| SCHEMBL30373812 | 0.75 | GPR119 (0.58) | CKS1BSKP1SKP2PRMT5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |