SCHEMBL305504

SCHEMBL305504

NCCC[Si](Oc1ccc(Cl)cc1)(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.40
LTA4H P09960 2/20 0.40
MAOB P27338 7/20 0.40
TAAR1 Q96RJ0 1/20 0.38
MAOA P21397 1/20 0.36
KIF11 P52732 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GBA1 P04062 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305461 0.80 TAAR1 (0.43) LTA4HTAAR1MAOA
SCHEMBL11996478 0.77 HPGD (0.43) KMT2ANPC1RAB9A
SCHEMBL1249273 0.71 MAOB (0.53) KCNH2MAOB
SCHEMBL305531 0.70 LMNA (0.38) KCNH2TAAR1CYP2D6MEN1KMT2A
SCHEMBL10863992 0.70 TAAR1 (0.38) KCNH2LTA4HTAAR1MAOAKIF11
SCHEMBL4028552 0.69 ALDH3A1 (0.53) KCNH2MAOB
Hydrochloric Acid SCHEMBL1534353 0.69 MAOB (0.55) KCNH2MAOB
SCHEMBL4027268 0.68 HRH3 (0.53) KCNH2MAOB
SCHEMBL4024224 0.68 HRH3 (0.53) KCNH2MAOB
SCHEMBL3705860 0.68 HRH3 (0.53) KCNH2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US claimed
EP-2173491-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2010-04-14 EP claimed
EP-2040847-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2009-04-01 EP claimed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO claimed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US claimed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO claimed
US-9567655-B2 Processes for the separation of ores GEORGIA-PACIFIC CHEMICALS LLC (US) 2017-02-14 US disclosed
WO-2014066237-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-05-01 WO disclosed
US-20140110621-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-24 US disclosed
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US disclosed
US-8092686-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-01-10 US disclosed
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US disclosed
US-7913852-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-03-29 US disclosed
EP-1838451-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC RESINS, INC. (US) 2007-10-03 EP disclosed
US-20070000839-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2007-01-04 US disclosed
US-20060151360-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2006-07-13 US disclosed
WO-2006071672-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2006-07-06 WO disclosed
US-4474636-A FURAN RESINS, HYDROXYMETHYLFURFURAL QO CHEMICALS, INC. (US) 1984-10-02 US disclosed
US-4331583-A Catalysts for foundry core binders THE QUAKER OATS COMPANY (US) 1982-05-25 US disclosed
US-4083817-A Blends of furan-aldehyde resins with phenolic resins and molded articles produced therefrom THE QUAKER OATS COMPANY (US) 1978-04-11 US disclosed