SCHEMBL305531

SCHEMBL305531

NCCC[Si](Oc1ccccc1Cl)(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
DPP4 P27487 1/20 0.38
TAAR1 Q96RJ0 2/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 1/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SLC2A1 P11166 1/20 0.35
PNMT P11086 1/20 0.35
HTR1B P28222 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 1/20 0.34
KCNH2 Q12809 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305461 0.73 TAAR1 (0.43) TAAR1
SCHEMBL1249120 0.73 HTR1B (0.56) SMN1; SMN2NPC1RAB9AL3MBTL1MEN1
SCHEMBL8962061 0.72 ALDH1A1 (0.42) LMNAMAPTTDP1KDM4EKCNH2
Hydrochloric Acid SCHEMBL14830577 0.72 KDM4E (0.57) SMN1; SMN2NPC1RAB9AL3MBTL1MEN1
SCHEMBL11708352 0.72 L3MBTL1 (0.59) SMN1; SMN2NPC1RAB9AL3MBTL1MEN1
SCHEMBL305504 0.70 KCNH2 (0.40) TAAR1NPC1RAB9AMEN1KMT2A
SCHEMBL7975151 0.70 L3MBTL1 (0.57) SMN1; SMN2NPC1RAB9AL3MBTL1MEN1
SCHEMBL1032880 0.67 KDM4E (0.68) SMN1; SMN2TAAR1NPC1RAB9AL3MBTL1
SCHEMBL7769417 0.66 TSHR (0.53) LMNASMN1; SMN2DPP4TAAR1L3MBTL1
SCHEMBL31036947 0.66 LMNA (0.42) LMNASMN1; SMN2NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US claimed
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US claimed
EP-2173491-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2010-04-14 EP claimed
EP-2040847-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2009-04-01 EP claimed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO claimed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US claimed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO claimed
US-9567655-B2 Processes for the separation of ores GEORGIA-PACIFIC CHEMICALS LLC (US) 2017-02-14 US disclosed
US-20140110621-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-24 US disclosed
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US disclosed
US-8092686-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-01-10 US disclosed
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US disclosed
US-7913852-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-03-29 US disclosed
US-20070000839-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2007-01-04 US disclosed
US-20060151360-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2006-07-13 US disclosed
WO-2006071672-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2006-07-06 WO disclosed
US-4543374-A Furan foundry binder system containing a curing promoter QO CHEMICALS, INC. (US) 1985-09-24 US disclosed
US-4543373-A NO-BAKE SAND CORES OR MOLDS QO CHEMICALS, INC. (US) 1985-09-24 US disclosed
US-4474636-A FURAN RESINS, HYDROXYMETHYLFURFURAL QO CHEMICALS, INC. (US) 1984-10-02 US disclosed
US-4083817-A Blends of furan-aldehyde resins with phenolic resins and molded articles produced therefrom THE QUAKER OATS COMPANY (US) 1978-04-11 US disclosed