Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507610 | 1.00 | NRP1 (0.48) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL30552516 | 0.96 | ACE (0.49) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL29607850 | 0.95 | OPRM1 (0.49) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL29872595 | 0.95 | NRP1 (0.54) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL34464910 | 0.95 | ACE (0.47) | NRP1OPRM1OPRK1ACEF2 | |
| SCHEMBL30422984 | 0.95 | ACE (0.47) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL29906667 | 0.93 | NRP1 (0.52) | NRP1OPRM1OPRK1NTSR2NTSR1 | |
| SCHEMBL30672574 | 0.93 | ACE (0.46) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL30490593 | 0.93 | OPRK1 (0.45) | NRP1OPRM1OPRK1ACENTSR2 | |
| SCHEMBL29802045 | 0.91 | OPRK1 (0.49) | NRP1OPRM1OPRK1ACENTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217571-B1 | Gene therapy by small fragment homologous replacement | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-05-15 | — | — | US | disclosed |
| EP-0636028-B1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING AN AMPHIPHATIC CATIONIC PEPTIDE | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-0708637-B1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | UNIV CALIFORNIA (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1236473-A2 | Self-assembling polynucleotide delivery system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-09-04 | — | — | EP | disclosed |
| US-6113946-A | EUKARYOTIC CELL, POLYNUCLEOTIDE AND DENDRIMER POLYCATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-05 | — | — | US | disclosed |
| US-6010908-A | IN SITU REPLACEMENT OF AN EXON CARRYING AN ENDOGENOUS TARGETED MUTANT DNA SEQUENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-01-04 | — | — | US | disclosed |
| US-5990089-A | INTRODUCING A POLYNUCLEOTIDE INTO A EUKARYOTIC CELL IN A LIVING ANIMAL COMPRISING CONTACTING THE CELL WITH A COMPOSITION COMPRISING A POLYNUCLEOTIDE AND A DENDRIMER POLYCATION COUPLED TO THE POLYNUCLEOTIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0636028-A4 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM. | UNIV CALIFORNIA (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0708637-A4 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | UNIV CALIFORNIA (US) | 1998-08-12 | — | — | EP | disclosed |
| CN-1178797-A | Oligopeptide derivative containing alpha, gamma-diaminobutanoic acid | HOFFMANN LA ROCHE (CH) | 1998-04-15 | — | — | CN | disclosed |
| EP-0834572-A2 | Alpha, gamma-diaminobutyric acid (DAB) containing oligopeptide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| EP-0656747-A4 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION. | UNIV CALIFORNIA (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0708637-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0656747-A1 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0636028-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1995002397-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-01-26 | — | — | WO | disclosed |
| WO-1994004032-A1 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993019768-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-10-14 | — | — | WO | disclosed |