Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210442 | 0.81 | AURKA (0.32) | AURKACYP11B1CYP11B2 | |
| SCHEMBL30552875 | 0.77 | AURKA (0.30) | AURKA | |
| SCHEMBL22405796 | 0.75 | ALDH1A1 (0.38) | AURKACYP11B1CYP11B2 | |
| SCHEMBL28916303 | 0.75 | AURKA (0.39) | AURKACYP11B1CYP11B2 | |
| SCHEMBL28916306 | 0.71 | AURKA (0.32) | AURKACYP11B1CYP11B2 | |
| SCHEMBL29286714 | 0.71 | ALDH1A1 (0.37) | AURKACYP11B1CYP11B2 | |
| SCHEMBL25433636 | 0.71 | AURKA (0.34) | AURKACYP11B1CYP11B2 | |
| SCHEMBL27865251 | 0.68 | AURKA (0.41) | AURKACYP11B1CYP11B2 | |
| SCHEMBL3847403 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL28916239 | 0.66 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482583-B1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2026-04-01 | — | — | EP | disclosed |
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-06-05 | — | — | US | disclosed |
| EP-4482583-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-01-01 | — | — | EP | disclosed |
| WO-2023161316-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | MRPL21, WIZ, CFTR | AURKA 1565/4885CYP11B1 1716/4885CYP11B2 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.