SCHEMBL3055304

SCHEMBL3055304

Cn1c([S+](C)[O-])ccc(C(=O)C2=C(O)CCCC2=O)c1=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3055280 0.77 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL3049026 0.77 SMN1; SMN2 (0.39) SMN1; SMN2KDM4E
SCHEMBL3046042 0.76 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL1372388 0.72 DAO (0.50) SMN1; SMN2KDM4E
SCHEMBL1373985 0.70 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL455164 0.67 SMN1; SMN2 (0.36) SMN1; SMN2KDM4E
SCHEMBL8588451 0.66 SMN1; SMN2 (0.54) SMN1; SMN2KDM4E
SCHEMBL20664806 0.66 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL22946327 0.64 SMN1; SMN2 (0.37) SMN1; SMN2KDM4E
SCHEMBL30230494 0.64 SMN1; SMN2 (0.40) SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1982978-B1 PYRIDONE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 2014-08-27 EP disclosed
US-8076487-B2 Pyridone derivative and herbicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2011-12-13 US disclosed
US-20100222592-A1 Pyridone Derivative and Herbicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-09-02 US disclosed
EP-1982978-A1 PYRIDONE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222592-A1 Pyridone Derivative and Herbicide PDXK, PNPO, CBR3 SMN1; SMN2 3804/4885KDM4E 1335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.