Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049026 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBAPOBEC3AAPOBEC3GTDP1 | |
| SCHEMBL3046042 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2POLBAPOBEC3AAPOBEC3GTDP1 | |
| SCHEMBL3055304 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL1372388 | 0.74 | DAO (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3047967 | 0.72 | MCL1 (0.41) | SMN1; SMN2LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL3048628 | 0.71 | GABRG2 (0.44) | TDP1L3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL1373985 | 0.69 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNA | |
| SCHEMBL8588451 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBAPOBEC3AAPOBEC3GTDP1 | |
| SCHEMBL23729701 | 0.66 | HPD (0.39) | SMN1; SMN2 | |
| SCHEMBL13475930 | 0.66 | SMN1; SMN2 (0.34) | SMN1; SMN2POLBAPOBEC3AAPOBEC3GTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982978-B1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-08-27 | — | — | EP | disclosed |
| US-8076487-B2 | Pyridone derivative and herbicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100222592-A1 | Pyridone Derivative and Herbicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-02 | — | — | US | disclosed |
| EP-1982978-A1 | PYRIDONE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222592-A1 | Pyridone Derivative and Herbicide | PDXK, PNPO, CBR3 | SMN1; SMN2 3804/4885POLB 4422/4885APOBEC3A 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.