Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700705 | 0.89 | ALOX5AP (0.43) | EPHX2ERAP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL15009785 | 0.89 | ALOX5AP (0.43) | EPHX2ERAP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30214832 | 0.80 | KIF11 (0.47) | EPHX2KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL2182720 | 0.80 | KIF11 (0.47) | EPHX2KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL17927016 | 0.79 | DDR1 (0.43) | EPHX2 | |
| SCHEMBL310121 | 0.79 | ALDH1A1 (0.43) | EPHX2ERAP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL27872324 | 0.79 | EPHX2 (0.43) | EPHX2ERAP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30214735 | 0.79 | ALDH1A1 (0.43) | EPHX2ERAP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL23203438 | 0.78 | KCNJ6 (0.49) | EPHX2ERAP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30994933 | 0.78 | ALOX5AP (0.46) | EPHX2ERAP1ALDH1A1L3MBTL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654326-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2025-03-18 | — | — | CN | disclosed |