Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310121 | 1.00 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL308729 | 0.85 | TRPV4 (0.42) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL30214832 | 0.83 | KIF11 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL2182720 | 0.83 | KIF11 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL30700705 | 0.81 | ALOX5AP (0.43) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL15009785 | 0.81 | ALOX5AP (0.43) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL27872324 | 0.81 | EPHX2 (0.43) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL30161533 | 0.79 | TRPV4 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL941069 | 0.79 | TRPV4 (0.47) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL29683114 | 0.79 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025279-A | Compounds capable of modulating endoplasmic reticulum aminopeptidase 1 | 格雷沃尔夫治疗有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4392414-A1 | INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-112236416-B | Pyrimidine cyclohexenyl glucocorticoid receptor modulators | 科赛普特治疗公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2023028534-A1 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |