SCHEMBL30553433

SCHEMBL30553433

CCn1ccnc1S(=O)(=O)Nc1cccc2c(-c3ccccc3)ccnc12

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CKS1B P61024 7/20 0.50
▸ SKP2 Q13309 7/20 0.50
▸ GLO1 Q04760 7/20 0.50
▸ SLC40A1 Q9NP59 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26964180 1.00 CKS1B (0.50) CKS1BSKP2GLO1SLC40A1
SCHEMBL30925426 0.85 SLC40A1 (0.48) CKS1BSKP2SLC40A1
SCHEMBL27214204 0.84 SLC40A1 (0.47) SLC40A1
SCHEMBL26964494 0.82 SLC40A1 (0.62) GLO1SLC40A1
SCHEMBL30553450 0.82 SLC40A1 (0.62) GLO1SLC40A1
SCHEMBL26964597 0.81 SLC40A1 (0.53) CKS1BSKP2SLC40A1
SCHEMBL30925440 0.79 GLO1 (0.56) CKS1BSKP2GLO1SLC40A1
SCHEMBL27214285 0.79 GLO1 (0.56) CKS1BSKP2GLO1SLC40A1
SCHEMBL30925474 0.78 SLC40A1 (0.60) CKS1BSKP2GLO1SLC40A1
SCHEMBL30925523 0.78 SLC40A1 (0.59) CKS1BSKP2GLO1SLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ZOETIS LLC 2024-05-09 — — US disclosed
CN-116806218-A Sulfonamide and its use for the treatment of parasitic helminth infections and diseases 新基公司 2023-09-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148744-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES ARSA, MRPS2, SULT2A1 CKS1B 2287/4885SKP2 2599/4885GLO1 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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