Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 3/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.46 |
| ▸ | FLT1 | P17948 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30554022 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ATP53OPRM1 | |
| SCHEMBL1593910 | 0.89 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL30554031 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ATP53OPRM1 | |
| SCHEMBL12803808 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AFLT1KDR | |
| SCHEMBL30554030 | 0.88 | OPRD1 (0.51) | SMN1; SMN2NPC1RAB9ATP53OPRM1 | |
| SCHEMBL30554002 | 0.86 | LMNA (0.48) | SMN1; SMN2NPC1RAB9ATP53OPRM1 | |
| SCHEMBL28415984 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ATP53OPRM1 | |
| SCHEMBL22310229 | 0.86 | RAB9A (0.56) | SMN1; SMN2NPC1RAB9ATP53OPRD1 | |
| SCHEMBL28700028 | 0.86 | USP2 (0.51) | SMN1; SMN2NPC1RAB9AFLT1KDR | |
| SCHEMBL28710568 | 0.83 | MAPT (0.51) | SMN1; SMN2NPC1RAB9ATP53OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187218-B | Application of 1-substituted-1H-imidazole-2-carboxylic acid compound in preparation of metal beta-lactamase inhibitor | 四川大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111253317-B | 1-substituted-1H-imidazole-2-carboxylic acid compound | 四川大学 | 2023-08-04 | — | — | CN | disclosed |