Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20719769 | 1.00 | KDM4E (0.40) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL31037762 | 0.81 | P4HTM (0.63) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10165320 | 0.80 | GABRG2 (0.44) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL23361737 | 0.79 | GABRG2 (0.43) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL18172756 | 0.79 | GABRG2 (0.43) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL19556246 | 0.78 | NR1H2 (0.42) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL30112027 | 0.78 | NR1H2 (0.42) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL19555927 | 0.78 | KDM4E (0.40) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL27718312 | 0.75 | TSHR (0.51) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL20943263 | 0.74 | ALDH1A1 (0.54) | MEN1ALDH1A1LMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447058-B1 | NOVEL BROAD-SPECTRUM BETA-LACTAMASE INHIBITOR | WUHAN VISION PHARMACEUTICAL TECH CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |