Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.53 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557529 | 0.96 | GRM7 (0.57) | CTSLAVPR2GRM7ALDH1A1KDM4E | |
| SCHEMBL3103616 | 0.96 | GRM7 (0.57) | CTSLAVPR2GRM7ALDH1A1KDM4E | |
| SCHEMBL30557602 | 0.92 | NOTUM (0.56) | CTSLALDH1A1CTSKLMNAKMT2A | |
| SCHEMBL25937485 | 0.82 | SIGMAR1 (0.45) | CTSLGRM7ALDH1A1NR1I3LMNA | |
| SCHEMBL18688679 | 0.81 | TSHR (0.55) | ALDH1A1CTSKLMNAKMT2AMEN1 | |
| SCHEMBL27004712 | 0.81 | CTSK (0.49) | CTSLGRM7ALDH1A1CTSKKMT2A | |
| SCHEMBL25430592 | 0.81 | GRM7 (0.63) | AVPR2GRM7ALDH1A1KDM4EPOLB | |
| SCHEMBL30557646 | 0.81 | BRD4 (0.48) | CTSLGRM7ALDH1A1KDM4EKMT2A | |
| SCHEMBL30557523 | 0.81 | CHRM2 (0.46) | CTSLGRM7ALDH1A1POLBCTSK | |
| SCHEMBL25937592 | 0.81 | CHRM2 (0.46) | CTSLGRM7ALDH1A1POLBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |