Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26784357 | 0.85 | KCNH2 (0.44) | TAAR1HTTALDH1A1NPSR1 | |
| SCHEMBL30557664 | 0.80 | CYP11B1 (0.35) | COMTSLC5A2CYP19A1 | |
| SCHEMBL22624611 | 0.80 | KLKB1 (0.35) | SLC5A2LTA4HHTTALDH1A1NPSR1 | |
| SCHEMBL30516652 | 0.79 | MAPT (0.43) | TAAR1HTTALDH1A1LMNA | |
| SCHEMBL30557723 | 0.76 | HSD17B1 (0.42) | SLC5A2CYP19A1PTGS1 | |
| SCHEMBL30557659 | 0.75 | PSMB5 (0.37) | — | |
| SCHEMBL13210488 | 0.75 | IDH1 (0.41) | TAAR1LTA4HALDH1A1GAAIDO1 | |
| SCHEMBL30557622 | 0.74 | BACE1 (0.42) | SLC5A2 | |
| SCHEMBL11611700 | 0.74 | LTA4H (0.54) | TAAR1LTA4HHTTCYP19A1ABCC4 | |
| SCHEMBL25367591 | 0.70 | LTA4H (0.42) | COMTTAAR1LTA4HHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158221-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS | 주식회사 카나프테라퓨틱스 | 2023-08-24 | — | — | WO | disclosed |