Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557698 | 0.79 | COMT (0.41) | ALDH1A1TAAR1LMNAHTT | |
| SCHEMBL13210488 | 0.77 | IDH1 (0.41) | ALDH1A1TAAR1NPC1 | |
| SCHEMBL11295155 | 0.72 | MAPT (0.41) | MAPTKMT2AMEN1ALDH1A1TAAR1 | |
| SCHEMBL30557659 | 0.72 | PSMB5 (0.37) | KMT2AMEN1 | |
| SCHEMBL30557723 | 0.70 | HSD17B1 (0.42) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28293841 | 0.69 | ALDH1A1 (0.62) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7999187 | 0.69 | — | — | |
| SCHEMBL11303064 | 0.68 | MAPK1 (0.47) | MAPTKMT2AMEN1ALDH1A1TAAR1 | |
| SCHEMBL24029803 | 0.68 | SLC5A1 (0.46) | MAPTKMT2AMEN1TAAR1RAB9A | |
| SCHEMBL13339388 | 0.68 | SLC6A2 (0.38) | MAPTKMT2AMEN1ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |