Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 2/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26643264 | 0.97 | THRB (0.34) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL24600451 | 0.95 | THRB (0.31) | BMPR1BBMPR1AACVRL1ACVR1THRB | |
| SCHEMBL29066215 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL26643453 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL24407922 | 0.79 | THRB (0.48) | THRB | |
| SCHEMBL29526743 | 0.79 | THRB (0.40) | THRBNPBWR1 | |
| SCHEMBL26643524 | 0.78 | PDE7A (0.37) | — | |
| SCHEMBL24600323 | 0.78 | PPOX (0.32) | NPBWR1 | |
| SCHEMBL24600445 | 0.78 | PDE4A (0.32) | NPBWR1 | |
| SCHEMBL24600252 | 0.74 | CREBBP (0.32) | NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710443-A | 2-pyridones as thyroid hormone receptor modulators | 阿利戈斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |