Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27436596 | 0.88 | DPP4 (0.55) | DPP4DPP8DPP9LNPEPERAP2 | |
| SCHEMBL30414989 | 0.84 | DPP8 (0.43) | DPP4DPP8DPP9LNPEPERAP2 | |
| SCHEMBL29729306 | 0.80 | SLC1A1 (0.42) | SLC1A1DPP4DPP8DPP9CTSD | |
| SCHEMBL27431340 | 0.78 | CD274 (0.42) | DPP4DPP8DPP9LNPEPERAP2 | |
| SCHEMBL27183214 | 0.78 | LNPEP (0.39) | DPP4DPP8DPP9LNPEPERAP2 | |
| SCHEMBL8213148 | 0.78 | LNPEP (0.39) | DPP4DPP8DPP9LNPEPERAP2 | |
| SCHEMBL14155398 | 0.76 | SLC1A1 (0.53) | SLC1A1DPP4DPP8DPP9TSHR | |
| SCHEMBL13379935 | 0.76 | BIRC2 (0.33) | TSHRBIRC2CA12CA1CA2 | |
| SCHEMBL131050 | 0.76 | SLC1A1 (0.55) | SLC1A1TSHRCA12CA1CA2 | |
| SCHEMBL131049 | 0.76 | SLC1A1 (0.55) | SLC1A1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704957-B2 | Composition for inhibiting HIV activity extracted from Paecilomyces sp. (Tochu-kaso) J300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2010-04-27 | — | — | US | disclosed |
| US-7704957-B2 | Composition for inhibiting HIV activity extracted from Paecilomyces sp. (Tochu-kaso) J300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2010-04-27 | — | — | US | disclosed |
| US-7704957-B2 | Composition for inhibiting HIV activity extracted from Paecilomyces sp. (Tochu-kaso) J300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2010-04-27 | — | — | US | disclosed |
| US-20040121963-A1 | Composition for inhibiting hiv activity extracted from paecilomyces sp. (tochu-kaso) j300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2004-06-24 | — | — | US | disclosed |
| EP-1389111-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM i PAECILOMYCES SP. /i (TOCHU-KASO) J300 | Republic of Korea (KR) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002080921-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM PAECILOMYCES SP. (TOCHU-KASO) J300 | REPUBLIC OF KOREA (KR) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121963-A1 | Composition for inhibiting hiv activity extracted from paecilomyces sp. (tochu-kaso) j300 | KMO, JMJD1C, KYAT3 | SLC1A1 879/4885DPP4 1684/4885DPP8 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.