SCHEMBL30561502

SCHEMBL30561502

C[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)CN)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.40
▸ OPRD1 P41143 4/20 0.40
▸ FAP Q12884 3/20 0.38
▸ PREP P48147 2/20 0.37
▸ DPP4 P27487 1/20 0.37
▸ BDKRB2 P30411 2/20 0.37
▸ APLNR P35414 1/20 0.36
▸ KMT2A Q03164 1/20 0.35
▸ XIAP P98170 1/20 0.35
▸ MLX Q9UH92 1/20 0.35
▸ NAA50 Q9GZZ1 1/20 0.34
▸ RAMP1 O60894 1/20 0.34
▸ CALCRL Q16602 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30558194 0.89 FAP (0.40) FAPPREPDPP4APLNRXIAP
SCHEMBL31751644 0.85 OPRM1 (0.43) OPRM1OPRD1FAPPREPDPP4
SCHEMBL30558187 0.84 FAP (0.42) FAPPREPDPP4APLNRXIAP
SCHEMBL30918796 0.84 OPRM1 (0.45) OPRM1OPRD1APLNRRAMP1CALCRL
SCHEMBL30028652 0.84 ITGB1 (0.43) OPRM1OPRD1FAPPREPKMT2A
SCHEMBL29691873 0.83 CAPN1 (0.47) OPRM1OPRD1BDKRB2APLNR
SCHEMBL30139051 0.82 OPRM1 (0.44) OPRM1OPRD1FAPPREPDPP4
SCHEMBL30138993 0.82 OPRM1 (0.42) OPRM1OPRD1RAMP1CALCRL
SCHEMBL30099452 0.82 KMT2A (0.40) OPRD1FAPAPLNRKMT2ANAA50
SCHEMBL31399252 0.82 APLNR (0.49) OPRM1OPRD1APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272030-A1 INSULIN-FC FUSION PROTEIN AND APPLICATION THEREOF JIANGSU GENSCIENCES INC. (CN) 2023-08-31 — — US disclosed
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